- By masteradmin
- February 06, 2020
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- Health
- Cancer
- Digestion support
- Fibrocystic breast disease
- Food allergies
- Hardening of the arteries (atherosclerosis)
- Hepatitis C
- Herpes zoster (shingles)
- Inflammation, sports injuries and trauma
- Pancreatic insufficiency
- Multiple sclerosis
- Rheumatoid arthritis and other autoimmune disorders
- Sinusitis, asthma, bronchitis, and chronic obstructive pulmonary disease
Proteolytic enzymes in cancer therapy
What clinical research has been done with proteolytic enzymes in cancer?
Are proteolytic enzymes actually absorbed?
Yes. One of the outdated arguments against the effectiveness of orally administered proteolytic enzymes was that they either got digested or they were too large to be absorbed. Absorption studies with the various proteolytic enzymes have confirmed that they are absorbed intact. In fact, they appear to be actively transported across the gut wall.3
Since stomach acid can destroy proteolytic enzymes, the best formulas are “enteric coated” tablets or “delayed release” capsules. Enteric-coating means that the pills have a coating around them to prevent the pill from being broken down in the stomach. An enteric-coated pill passes into the small intestine, where due to the pH change it will break down there. One of the problems with enteric-coating is that unwanted synthetic compounds are often used in the film coating. A better approach is to use “delayed release” vegetarian capsules that use natural dietary fibers that also resist stomach acid to provide targeted delivery of the enzymes to the upper small intestine.
Can taking proteolytic enzymes actually improve digestion?
Do the proteolytic enzymes digest blood proteins?
How do the proteolytic enzymes help autoimmune conditions like rheumatoid arthritis?
The benefits in some inflammatory conditions appears to be related to helping the body breakdown immune complexes formed between antibodies produced by the immune system and the compounds they bind to (antigens). Conditions associated with high levels of immune complexes in the blood are often referred to as “autoimmune diseases” and include such diseases as rheumatoid arthritis, lupus, scleroderma, and multiple sclerosis. Higher levels of circulating immune complexes are also seen in ulcerative colitis, Crohn’s disease, and AIDS.4-6
What other conditions might proteolytic enzymes be helpful for?
What proteolytic enzyme product do you recommend?
- Bromelain 1200 GDU
- Protease 130,000 HUT
- Papain 3,000,000 PU
- Serrapeptase 80,000 SPU
The Miracle Enzyme
Condition | Cases | % Effectiveness |
Post-surgical swelling | 742 | 88.5% |
Sports injuries/trauma | 208 | 87.5% |
Inflammatory disease | 906 | 77% |
COPD/Bronchitis | 556 | 74% |
Enhancement of antibiotic | 124 | 79% |
ENT infection and inflammation | 140 | 97.3% |
Fibrocystic breast disease | 70 | 85.7% |
What is the proper dosage of proteolytic enzymes?
Are proteolytic enzymes preparations safe?
Proteolytic enzymes are generally well-tolerated and are not associated with any significant side effects. Even in people with presumably normal pancreatic function, taking proteolytic enzymes produced no untoward side effects nor did it reduce the capacity for these subjects to produce their own pancreatic enzymes.14 However, my recommendation is to utilize these preparations only when there is apparent need.
Although no significant side effects have been noted with any of the proteolytic enzymes, allergic reactions may occur (as with most therapeutic agents). Pancreatic enzymes should not be used by anyone allergic to pork; bromelain should not be used in anyone allergic to pineapple; and papain should not be used in anyone sensitive to papaya.
References:
- Gonzalez NJ, Isaacs LL: Evaluation of pancreatic proteolytic enzyme treatment of adenocarcinoma of the pancreas, with nutrition and detoxification support. Nutr Cancer 1999;33:117-24.
- Leipner J, Saller R: Systemic enzyme therapy in oncology: effect and mode of action. Drugs. 2000;59:769-80.
- Ambrus JL, et al.: Absorption of exogenous and endogenous proteolytic enzymes. Clin Pharmacol Therap 1967;8:362-8.
- Mazurov VI, et al. Beneficial effects of concomitant oral enzymes in the treatment of rheumatoid arthritis. Int J Tiss React 1997;19:91.
- Ransberger K: Enzyme treatment of immune complex diseases. Arthritis Rheuma 1986;8:16-9.
- Steffen C, et al.: Enzyme therapy in comparison with immune complex determinations in chronic polyarteritis. Rheumatologie 1985;44:51-6.
- Ransberger K, van Schaik W: Enzyme therapy in multiple sclerosis. Der Kassenarzt 1986;41:42-5.
- Kleine MW, et al.: The intestinal absorption of orally administered hydrolytic enzymes and their effects in the treatment of acute herpes zoster as compared with those of oral acyclovir therapy. Phytomedicine 1995;2:7-15.
- Kabil SM, Stauder G: Oral enzyme therapy in hepatitis C patients. Int J Tiss React 1997;19:97-8.
- Esch PM, Gerngross H, Fabian A: Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase-a prospective study (German). Fortschr Med. 1989;107(4):67-8, 71-2.
- Kee WH, et al.: The treatment of breast engorgement with Serrapeptase (Danzen): a randomized double-blind controlled trial. Singapore Med J 1989;30(1):48-54.
- Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990; 18(5):379-88.
- Majima Y, et al.: The effect of an orally administered proteolytic enzyme on the elasticity and viscosity of nasal mucus. Arch Otorhinolaryngol. 1988;244(6):355-9.
- Friess H, et al.: Influence of high-dose pancreatic enzyme treatment on pancreatic function in healthy volunteers. Int J Pancreatol 1998;23:115-23